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dc.contributor.authorEspindola, Foued S.-
dc.contributor.authorBanzi, Silmara R.-
dc.contributor.authorCalabria, Luciana K.-
dc.contributor.authorCustódio, Rodrigo J.-
dc.contributor.authorOliveira, Ricardo A.-
dc.contributor.authorProcópio, Leandro D.-
dc.contributor.authorLima, Andreia B. P.-
dc.contributor.authorCunha-Junior, Jair P.-
dc.contributor.authorCoelho, Milton V.-
dc.contributor.authorGuedes, Iêda M. L.-
dc.contributor.authorPellizzon, Cláudia H.-
dc.contributor.authorLarson, Roy E.-
dc.contributor.authorEspreafico, Enilza M.-
dc.identifier.citationCell and Tissue Research, v. 333, n. 2, p. 263-279, 2008.-
dc.description.abstractMyosin-Va is a Ca 2+/calmodulin-regulated unconventional myosin involved in the transport of vesicles, membranous organelles, and macromolecular complexes composed of proteins and mRNA. The cellular localization of myosin-Va has been described in great detail in several vertebrate cell types, including neurons, melanocytes, lymphocytes, auditory tissues, and a number of cultured cells. Here, we provide an immunohistochemical view of the tissue distribution of myosin-Va in the major endocrine organs. Myosin-Va is highly expressed in the pineal and pituitary glands and in specific cell populations of other endocrine glands, especially the parafollicular cells of the thyroid, the principal cells of the parathyroid, the islets of Langerhans of the pancreas, the chromaffin cells of the adrenal medulla, and a subpopulation of interstitial testicular cells. Weak to moderate staining has been detected in steroidogenic cells of the adrenal cortex, ovary, and Leydig cells. Myosin-Va has also been localized to non-endocrine cells, such as the germ cells of the seminiferous epithelium and maturing oocytes and in the intercalated ducts of the exocrine pancreas. These data provide the first systematic description of myosin-Va localization in the major endocrine organs of rat. © 2008 Springer-Verlag.en
dc.subjectEndocrine glands-
dc.subjectGerm cells-
dc.subjectNeuroendocrine cells-
dc.subjectRat (Wistar)-
dc.subjectmessenger RNA-
dc.subjectmyosin Va-
dc.subjectprotein kinase (calcium,calmodulin)-
dc.subjectadrenal cortex-
dc.subjectanimal cell-
dc.subjectanimal tissue-
dc.subjectcell specificity-
dc.subjectcell subpopulation-
dc.subjectcell type-
dc.subjectcellular distribution-
dc.subjectchromaffin cell-
dc.subjectcontrolled study-
dc.subjectendocrine cell-
dc.subjectLeydig cell-
dc.subjectmembrane vesicle-
dc.subjectnerve cell-
dc.subjectoocyte maturation-
dc.subjectovary cell-
dc.subjectpancreas islet-
dc.subjectparathyroid cell-
dc.subjectpineal body-
dc.subjectpriority journal-
dc.subjectprotein expression-
dc.subjectprotein localization-
dc.subjectseminiferous tubule epithelium-
dc.subjecttestis cell-
dc.subjectthyroid follicle cell-
dc.subjecttissue distribution-
dc.subjectAdrenal Glands-
dc.subjectEndocrine Glands-
dc.subjectIslets of Langerhans-
dc.subjectMyosin Heavy Chains-
dc.subjectMyosin Type V-
dc.subjectParathyroid Glands-
dc.subjectPineal Gland-
dc.subjectPituitary Gland-
dc.subjectThyroid Gland-
dc.subjectTissue Distribution-
dc.titleLocalization of myosin-Va in subpopulations of cells in rat endocrine organsen
dc.contributor.institutionUniversidade Federal de Uberlândia (UFU)-
dc.contributor.institutionUniversidade de São Paulo (USP)-
dc.contributor.institutionUniversidade Estadual Paulista (UNESP)-
dc.description.affiliationInstituto de Genética e Bioquímica Laboratório de Bioquímica e Biologia Molecular Universidade Federal de Uberlândia, Uberlândia, Minas Gerais-
dc.description.affiliationFaculdade de Medicina de Ribeirão Preto Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos Universidade de São Paulo, Ribeirão Preto, São Paulo-
dc.description.affiliationInstituto de Biociências Departamento de Morfologia Universidade Estadual de São Paulo, Botucatu, São Paulo-
dc.description.affiliationUnespInstituto de Biociências Departamento de Morfologia Universidade Estadual de São Paulo, Botucatu, São Paulo-
dc.rights.accessRightsAcesso restrito-
dc.relation.ispartofCell and Tissue Research-
Appears in Collections:Artigos, TCCs, Teses e Dissertações da Unesp

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